Yi Guan Jian: Herbal Support for Liver and Yin Health
- Health Lab
- Jan 30
- 4 min read
Updated: May 4
Yi Guan Jian, or Effective Integration Decoction, is a cherished Chinese herbal formula from Continuation of Famous Doctors' Cases. Renowned in traditional Chinese medicine (TCM) for nourishing yin and soothing the liver, this blend of six herbs addresses liver and kidney yin deficiency combined with liver qi stagnation.

It relieves symptoms like chest pain, acid reflux, and dry mouth, offering a gentle yet effective remedy for modern ailments like hepatitis and gastritis, rooted in centuries of healing wisdom.
What’s in Yi Guan Jian?
Yi Guan Jian combines six herbs, structured by the TCM principle of monarch, minister, assistant, and envoy, to nourish yin, soften the liver, and promote qi flow. The ingredients and their roles are:
Monarch Herb
Rehmannia Root (Sheng Di Huang): Sweet and cold, rehmannia nourishes yin and blood, strengthens the liver and kidneys, and relieves dryness.
Minister Herbs
Glehnia Root (Sha Shen): Sweet and cool, glehnia nourishes lung and stomach yin, boosting fluids to balance liver function.
Ophiopogon Root (Mai Dong): Sweet and cool, ophiopogon moistens the lungs and stomach, enhancing yin to support the liver.
Assistant Herbs
Angelica Root (Dang Gui): Sweet and warm, angelica nourishes blood, softens the liver, and improves circulation.
Wolfberry (Gou Qi Zi): Sweet and neutral, wolfberry nourishes liver and kidney yin, enriching blood and vitality.
Envoy Herb
Toosendan Fruit (Chuan Lian Zi): Bitter and cold, toosendan clears liver heat, unblocks qi stagnation, and relieves pain.
Preparation
Decoct the herbs in water and drink warm as a tea, typically taken for a few days or as prescribed, with dosages adjusted based on the patient’s condition.
How It Works
Yi Guan Jian targets liver and kidney yin deficiency with liver qi stagnation, a TCM condition where insufficient yin (moisture and nourishment) impairs liver function, causing qi to stagnate. This leads to symptoms like chest pain, acid reflux, or dry throat. The formula works by:
Nourishing Yin: Rehmannia, glehnia, and ophiopogon replenish yin fluids, hydrating the liver and kidneys.
Softening the Liver: Angelica and wolfberry nourish blood, making the liver more flexible and easing tension.
Unblocking Qi: Toosendan clears stagnant liver qi and heat, relieving pain and digestive upset.
Balancing the Five Elements: The herbs strengthen the lungs (metal) and stomach (earth) to regulate the liver (wood), promoting harmony.
This balanced approach nourishes without overloading the stomach, ensuring smooth liver function and emotional ease, as TCM teaches: “Nourish yin to soften the liver, and unblock qi to restore flow.”
What Does It Treat?
Yi Guan Jian is used for liver and kidney yin deficiency with liver qi stagnation, with symptoms including:
Chest or rib pain
Acid reflux or bitter vomiting
Dry throat or mouth
Red tongue with little moisture
Weak or thin pulse
Hernias or abdominal masses
These reflect a liver starved of yin and blocked by stagnant qi, often triggered by stress, poor diet, or chronic illness.

Pathogenesis in TCM
In TCM, the liver stores blood and ensures smooth qi flow, relying on yin for nourishment and yang for action. When liver and kidney yin are deficient, the liver lacks moisture, leading to stiffness and qi stagnation.
This can disrupt the stomach, causing acid reflux or pain, or block the liver meridian, forming hernias or masses. Insufficient yin also dries the throat and weakens the pulse. Yi Guan Jian restores yin, softens the liver, and clears stagnation, addressing both symptoms and root causes.
Modern Applications
Modern research highlights Yi Guan Jian’s anti-fibrotic, analgesic, and anti-inflammatory effects, driven by active compounds like saponins and flavonoids. Clinical uses include:
Liver Diseases: Treats chronic hepatitis, cirrhosis, and fatty liver by reducing fibrosis and protecting liver cells.
Digestive Disorders: Relieves chronic gastritis, gastric ulcers, and duodenal ulcers by soothing stomach pain and acid reflux.
Neurological Conditions: Eases intercostal neuralgia and neurasthenia by calming nerves and improving qi flow.
Systemic Conditions: Supports anemia, malnutrition, tuberculosis, and diabetes by nourishing yin and blood.
Other Benefits: Enhances stamina, reduces hypoxia, and clears cough or phlegm in chronic conditions.
Its ability to nourish without causing digestive heaviness makes it ideal for chronic yin-deficient disorders.
Precautions
Not for Phlegm or Stagnation: Avoid in cases of phlegm, fluid retention, or visible pathogens (e.g., greasy tongue coating, tight pulse).
Tongue and Pulse: Unsuitable for patients with no saliva, dirty tongue coating, or non-yin-deficient conditions (e.g., qi stagnation, excess heat).
Contraindications: Avoid in cases of fire hyperactivity, indigestion, or dampness without yin deficiency.
Conclusion
Yi Guan Jian is a masterful Chinese herbal formula that nourishes yin, soothes the liver, and restores balance. With rehmannia, glehnia, ophiopogon, and toosendan, it relieves chest pain, dry mouth, and liver-related ailments caused by yin deficiency and qi stagnation.
Widely used in modern TCM for hepatitis, gastritis, and neurological issues, its benefits are backed by research showing anti-fibrotic and calming effects. When used under professional guidance, Yi Guan Jian offers a gentle, nourishing path to liver health and vitality, embodying TCM’s timeless approach to healing.


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